Meta Cell Technology

Revolutionary PRP Treatment Method

Regenerative  ClinicΤΜ brings Meta Cell Technology (MCT®) to Greece for the first time. It is a revolutionary technology that dramatically improves the effectiveness of Platelet Rich Plasma (PRP) therapy, and takes it to the next step by unleashing the healing power of the exosomes contained in PRP. Exosomes redefine cellular activity and enhance cellular renewal at high performance levels.They are organic, effective and completely safe.

The Regenerative ClinicTM uses exclusively autologous products, which are produced from the patient’s own blood (blood draw) and after processing are injected into the patient in the same visit.

The main distinctive factor among autologous, allogeneic, and xenogeneic exosomes lies in their source. Autologous exosomes originate from cells of the same individual, allogeneic exosomes derive from cells of a different individual of the same species, and xenogeneic exosomes come from cells of a different species.

Autologous exosomes benefit from immune privilege, while heterologous exosomes are prone to triggering an immune response in the patient. The resulting immunogenic response contributes to the short-lived nature of heterologous exosomes, limiting their efficacy and therapeutic potential. Safety concerns also arise from the potential risk of cross- or intra-species contamination associated with the use of heterologous exosomes. All these factors position autologous exosomes as a valid medicinal therapeutic option, while heterologous exosomes are primarily confined to cosmetic applications.

Meta Cell Technology (MCT®)

Meta Cell Technology (MCT®) is a medical system that can improve any autologous product, such as PRP or stem cells concentrates, and stimulates the exosome production and deliverance.

Through photo- thermal energy it delivers extraordinary growth factor concentration and boosts/enhances cells, filling them with ATP and huge amounts of exosomes.

MCT autologous products stand out for their remarkably enhanced regenerative power, achieving tissue regenaration and improved clinical results.

Regenerative Clinic

Inspired technology. Excellent results.

MCT Unit®

MCT Unit® enables existing regenerative medicine treatments to be boosted, simply and quickly. Through the application of electromagnetic and thermal energy, it improves the general characteristics of autologous products, such as growth factor content, ATP production, and cell or platelet performance. It handles a wide range of temperatures and multiple wave lengths which are set up in comfortable one-touch protocols and customized programs.

MCT Kit®

MCT Kit® is a patented device with a specific shape and chemical composition, exclusively developed for photo-thermal conditioning. It is made of a medical grade polymer that guarantees optimal scattering, transmittance, and other optical properties, ensuring the emitted light will reach the target effectively. Its unique geometry grants an excellent surface/volume energy exposure ratio. MCT Kit® can allocate 10 mL of any autologous preparation.

MCT Plasma

… much more than PRP

MCT Plasma® is a state-of-the art regenerative product that is created by applying photothermal energy to PRP (platelet-rich plasma). This process stimulates the platelets and boosts growth factor release, resulting in faster and better outcomes.

PRP Photo biomodulation

Light provides a non-invasive, non-toxic way of stimulating cellular metabolism. Ultimately, the energy absorbed at the mitochondria enhances cellular ATP production. Photothermal-stimulation of PRP generates MCT Plasma®, a state-of-the-art regenerative preparation.

This vanguard autologous plasma achieves superb clinical results due to a more prolonged and sustained growth factors release and a reduced pro-inflammatory cytokine content. Its remarkable results lead the tissue regeneration process.

PRP Thermo biomodulation

As with the light, temperature has a huge body of evidence that backs up its effectiveness and safe utilization. Thermal stimulation prepares platelets to work more and better, increases their reactiveness and shows-up a myriad of activation markers. Platelet primed functionality also determines a huge increment in the release of growth factors.

Since thermal boosting delays the clot onset and primes platelet aggregation only after activation, MCT Plasma® results in a less dense regenerative product, implying the achievement of spectacular clinical results.

MCT Exosomes

… unleashing the power of exosomes

The possibility of generating, concentrating and administering  exosomes and other EVs signals a new era exponentially increasing the power of regenerative medicine  treatments.

MCT® exosomes goes one step beyond cells, achieving autologous injectable exosomes for medical use and awesome clinical results.

EXOSOMES and blue light

Blue light illumination improves therapeutic effect of exosomes. Elevated levels of miRNAs and mRNAs due to blue light exposure increase pro-angiogenic capacities in MSCs and MSCs exosomes. Blue opsin photo-transduction is an invaluable tool for cell regenerative power enhancement.

EXOSOMES and thermal energy

The frequency of exosome-cell membrane fusion events increases at higher temperatures. The kinetics of exosomes release is faster at higher temperatures.

A portion of exosomes are free to diffuse away from fusion site, but some remain attached. This process is temperature dependent with fewer exosomes remaining attached at higher temperatures.

TREATMENT PROTOCOLS

Typical Protocol

The typical protocol includes 3 sessions, with an interval of 3 weeks between sessions. Maintenance sessions are advised, according to individual needs ( at 3 and 6 months in moderate to severe cases).

Combined Protocol (MCT® PRP + Exosomes)

To augment therapeutic result, the combined protocol consists of administration of PRP and exosomes (two injections) during the same session. Three sessions of treatment are needed, with an interval of 3-4 weeks.